Login / Signup

Climate, human behaviour or environment: individual-based modelling of Campylobacter seasonality and strategies to reduce disease burden.

Stephen P RushtonRoy A SandersonPeter J DiggleMark D F ShirleyAlasdair P BlainIain LakeJames A MaasWilliam D K ReidJo HardstaffNicola WilliamsNatalia R JonesDaniel RigbyNorval J C StrachanKen J ForbesPaul R HunterThomas J HumphreySarah J O'Brien
Published in: Journal of translational medicine (2019)
This is the first interdisciplinary study to integrate environment, risk behaviour, socio-demographics and immunology to model Campylobacter infection, including pathways to mitigation. We conclude that vaccination is likely to be the best route for intervening against campylobacteriosis despite the technical problems associated with understanding both the underlying human immunology and genetic variation in the pathogen, and the likely cost of vaccine development.
Keyphrases
  • endothelial cells
  • climate change
  • induced pluripotent stem cells
  • mental health
  • pluripotent stem cells
  • antimicrobial resistance
  • staphylococcus aureus
  • pseudomonas aeruginosa