Transient receptor potential mucolipin 1 circumvents oxidative stress in primary human melanocytes.
Yi ChenBo XieYebei HuJiayi SunJinhui XuYuqing ShenYuqi ZhuXiuzu SongPublished in: Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) (2024)
TRPML1 might mediate lysosomal autophagy in primary human MCs under oxidative stress, participating in mechanisms that maintain the oxidative and antioxidant systems in balance.
Keyphrases
- oxidative stress
- endothelial cells
- dna damage
- induced pluripotent stem cells
- pluripotent stem cells
- ischemia reperfusion injury
- diabetic rats
- induced apoptosis
- cell death
- signaling pathway
- endoplasmic reticulum stress
- risk assessment
- brain injury
- blood brain barrier
- anti inflammatory
- subarachnoid hemorrhage
- heat shock
- binding protein
- cerebral ischemia
- heat shock protein