Diagnosis and Clinical Features of Perianal Lesions in Newly Diagnosed Crohn's Disease: Subgroup Analysis from Inception Cohort Registry Study of Patients with Crohn's Disease (iCREST-CD).
Takayuki YamamotoHiroshi NakaseKenji WatanabeShinichiro ShinzakiNoritaka TakatsuToshimitsu FujiiRyuichi OkamotoKatsuyoshi MatsuokaAkihiro YamadaReiko KunisakiMinoru MatsuuraHisashi ShigaShigeki BambaYohei MikamiTakahiro ShimoyamaSatoshi MotoyaTakehiro TorisuTaku KobayashiNaoki OhmiyaMasayuki SarutaKoichiro MatsudaTakayuki MatsumotoAtsuo MaemotoYoko MurataShinichi YoshigoeShinya NagasakaTsutomu YajimaTadakazu Hisamatsunull nullPublished in: Journal of Crohn's & colitis (2023)
At the time of CD diagnosis, approximately half of the patients had perianal lesions; perianal abscesses and perianal fistulas were the most common. Young age, male sex, disease location, and behaviour are significantly associated with the presence of perianal lesions. The presence of perianal lesion was associated with fatigue and impairment of daily activities.