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Comparing natural language processing representations of coded disease sequences for prediction in electronic health records.

Thomas BeaneySneha JhaAsem AlaaAlexander SmithJonathan ClarkeThomas WoodcockAzeem MajeedPaul P AylinMauricio Barahona
Published in: Journal of the American Medical Informatics Association : JAMIA (2024)
Patient representations produced by sequence-based NLP algorithms from sequences of disease codes demonstrate improved predictive content for patient outcomes compared with representations generated by co-occurrence-based algorithms. This suggests transformer models may be useful for generating multi-purpose representations, even without fine-tuning.
Keyphrases
  • working memory
  • electronic health record
  • machine learning
  • deep learning
  • clinical decision support
  • adverse drug
  • amino acid