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MesoTRAP: a feasibility study that includes a pilot clinical trial comparing video-assisted thoracoscopic partial pleurectomy decortication with indwelling pleural catheter in patients with trapped lung due to malignant pleural mesothelioma designed to address recruitment and randomisation uncertainties and sample size requirements for a phase III trial.

Claire MatthewsCarol FreemanLinda D SharplesJulia Fox-RushbyAngela TodNicholas A MaskellJohn G EdwardsAman S CoonarPasupathy SivasothyVictoria HughesNajib M RahmanDavid A WallerRobert Campbell Rintoul
Published in: BMJ open respiratory research (2019)
NCT03412357.
Keyphrases
  • phase iii
  • clinical trial
  • open label
  • phase ii
  • study protocol
  • double blind
  • placebo controlled
  • randomized controlled trial
  • urinary tract infection
  • robot assisted
  • minimally invasive
  • thoracic surgery