We examined a total of 106 patients with ischaemic heart disease (mean age - 59±7 years) and 30 apparently healthy people (mean age - 36±4 years). Myocardial revascularization was performed with the help of stenting and coronary artery bypass grafting. The patients with ischaemic heart disease were divided into 2 groups: Group 1 with postinfarction cardiosclerosis and Group 2 without Q-forming myocardial infarction. Echocardiography was performed using the Vivid E9 machine prior to operation, intraoperatively, and 10-14 after the intervention. We registered the end-systolic volume and end-diastolic volume of the left ventricle, ejection fraction, cardiac index. Alterations of velocity were assessed in relation to of the volume of the left ventricle (dVol/dt), length of the ventricle (dL/dt) in systole and diastole, as well as myocardial shift velocity in 3 endocardial regions - basal (V1), middle (V2), apical portions (V3) and interrelationship with intraventricular blood flows. It was determined that myocardial dysfunction leads to impairment of the structure of the flow, change of acceleration, which is accompanied by a decrease in the cardiac productivity. Impairment of segmental contractility of the left ventricle is manifested by a decrease of vectors of myocardial motion velocity by more than 20%. Intraventricular flows in cardiac chambers may serve as predictors of adequacy of correction of coronary pathology.
Keyphrases
- left ventricular
- aortic stenosis
- mitral valve
- coronary artery bypass grafting
- pulmonary hypertension
- cardiac resynchronization therapy
- coronary artery disease
- ejection fraction
- heart failure
- pulmonary artery
- coronary artery
- percutaneous coronary intervention
- randomized controlled trial
- blood flow
- congenital heart disease
- climate change
- blood pressure
- pulmonary arterial hypertension
- oxidative stress
- transcatheter aortic valve replacement
- mass spectrometry
- aortic valve
- smooth muscle