A Standardized, 3-Tiered, Seizure Burden-Based Protocol for the Treatment of Neonatal Seizures.
Ashley A MoellerAndrei R StefanescuBeatrice M StefanescuMeredith R GolombFrances A BoyleWilliam F BussRebecca S RoseSarah E WingPublished in: Journal of child neurology (2023)
Implementation of a standardized, 3-tiered protocol for treatment of neonatal seizures improved short-term outcomes. Although not measured directly, reductions in EEG duration and midazolam use are promising indicators of overall seizure burden. More research is needed to evaluate impact on long-term neurodevelopmental outcomes.