Efficacy of prophylactic pre-operative desmopressin administration during functional endoscopic sinus surgery for chronic rhinosinusitis: A systematic review and meta-analysis of randomised placebo-controlled trials.
Abdullah Abdulaziz AlrajhiAbdullah Shakhs AlghamdiMohammed Hassan BaaliAbdulaziz Fahad AltowairqiMeshal Fahad KhanAhmad Saad AlharthiEbraheem AlbazeeAhmed Abu-ZaidPublished in: Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery (2023)
Among patients undergoing FESS, prophylactic administration of desmopressin does not correlate with significant clinical benefits. Data on safety is limited. Future research may explore the synergistic antihaemorrhagic efficacy and safety of tranexamic acid (TXA) plus desmopressin versus TXA alone among patients undergoing FESS.
Keyphrases
- patients undergoing
- placebo controlled
- chronic rhinosinusitis
- double blind
- minimally invasive
- clinical trial
- study protocol
- coronary artery bypass
- open label
- phase ii
- electronic health record
- ultrasound guided
- current status
- big data
- randomized controlled trial
- cancer therapy
- machine learning
- atrial fibrillation
- rectal cancer
- artificial intelligence
- endoscopic submucosal dissection