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Structures of EccB1 and EccD1 from the core complex of the mycobacterial ESX-1 type VII secretion system.

Jonathan M WagnerSum ChanTimothy J EvansSara KahngJennifer KimMark A ArbingDavid EisenbergKonstantin V Korotkov
Published in: BMC structural biology (2016)
These structures represent a major step towards resolving the molecular architecture of the entire ESX-1 assembly and may contribute to ESX-1 targeted tuberculosis intervention strategies.
Keyphrases
  • mycobacterium tuberculosis
  • high resolution
  • randomized controlled trial
  • cancer therapy
  • pulmonary tuberculosis
  • hiv aids
  • emergency department
  • drug delivery
  • mass spectrometry
  • adverse drug
  • hiv infected