Peptidylarginine Deiminases Inhibitors Decrease Endothelial Cells Angiogenic Potential by Affecting Akt Signaling and the Expression and Secretion of Angiogenic Factors.

Oskar CiesielskiLuciano PirolaAneta Balcerczyk

Published in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology (2024)

Our findings suggest that pharmacological inhibitors of citrullination are promising therapeutic agents to target angiogenesis.

Keyphrases

endothelial cells
poor prognosis
signaling pathway
cell proliferation
high glucose
human health
risk assessment