The oncogenic role of HIF-1α/miR-182-5p/ZFP36L1 signaling pathway in nasopharyngeal carcinoma.

Gang WangFangzheng ZhouTong OuHaiyan SunZhirui ShanYingshen LuGui ChenSimin YuanXiaowen ZhangSong Wu

Published in: Cancer cell international (2021)

Our data suggests that miR-182-5p facilitates cell proliferation and migration in NPC through its ability to down-regulate ZFP36L1 expression, and that the HIF-1α/miR-182-5p/ZFP36L1 axis may serve as a novel therapeutic target in the management of NPC.

Keyphrases

signaling pathway
poor prognosis
endothelial cells
single cell
electronic health record
pi k akt
cell therapy
big data
epithelial mesenchymal transition
transcription factor
binding protein
induced apoptosis
stem cells
long non coding rna
artificial intelligence
mesenchymal stem cells