Performance analysis of novel toxin-antidote CRISPR gene drive systems.

Jackson ChamperIsabel K KimSamuel E ChamperAndrew G ClarkPhilipp W Messer

Published in: BMC biology (2020)

Overall, our results suggest that CRISPR-based TA gene drives provide promising candidates for flexible ecological engineering strategies in a variety of organisms.

Keyphrases

genome wide
crispr cas
genome editing
copy number
dna methylation
escherichia coli
genome wide identification
gene expression
transcription factor