Perineural invasion by prostate adenocarcinoma in needle biopsies predicts bone metastasis: Ten year data from the TROG 03.04 RADAR Trial.
Brett DelahuntJudith D MurrayAllison SteiglerChris AtkinsonDavid ChristieGillian DuchesneLars EgevadDavid JosephJohn MatthewsChristopher OldmeadowHemamali SamaratungaNigel A SpryJohn R SrigleyHubert HondermarckJames W DenhamPublished in: Histopathology (2020)
The association between PNI and the development of bone metastases supports the inclusion of this parameter as a component of the routine histology report. Further this association suggests that evaluation of PNI may assist in selecting those patients who should be monitored more closely during follow-up.
Keyphrases
- ultrasound guided
- prostate cancer
- bone mineral density
- study protocol
- squamous cell carcinoma
- electronic health record
- phase iii
- cell migration
- clinical practice
- clinical trial
- phase ii
- big data
- locally advanced
- soft tissue
- randomized controlled trial
- bone regeneration
- open label
- postmenopausal women
- body composition
- rectal cancer