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Genome-resolved metaproteomic characterization of preterm infant gut microbiota development reveals species-specific metabolic shifts and variabilities during early life.

Weili XiongChristopher T BrownMichael J MorowitzJillian F BanfieldRobert L Hettich
Published in: Microbiome (2017)
Overall, this study reports species-specific proteome profiles and metabolic functions of human gut microbiota during early colonization. In particular, our work contributes to reveal microbiota-associated shifts and variations in the metabolism of three major nutrient sources and short-chain fatty acid during colonization of preterm infant gut.
Keyphrases
  • early life
  • fatty acid
  • low birth weight
  • endothelial cells
  • preterm birth
  • genome wide
  • gestational age
  • drinking water
  • induced pluripotent stem cells
  • preterm infants
  • single cell
  • gene expression
  • dna methylation