Development of a Bile Acid-Related Gene Signature for Predicting Survival in Patients with Hepatocellular Carcinoma.
Gang WangJun GuanQin YangFengtian WuJunwei ShaoQihui ZhouZixuan GuoYanli RenHaihong ZhuZhi ChenPublished in: Computational and mathematical methods in medicine (2022)
The three-gene prediction model was more reliable than the pathological staging characters of the tumor for the prognosis and survival of patients with HCC. In addition, the upregulated genes facilitating the transport of BAs are associated with poor prognosis of patients with HCC, and genes of de novo synthesis of BAs benefit patients with HCC.