The Analysis of bcl-2 in Association with p53 and Ki-67 in Triple Negative Breast Cancer and Other Molecular Subtypes in Ghana.

Charity Ameh-MensahBabatunde Moses DuduyemiKweku Bedu-AddoElijah Atta Manu Francis OpokuNicholas Titiloye

Published in: Journal of oncology (2021)

Our results show high expression of bcl-2 (protein) suggesting an important role of apoptosis in Ghanaian breast cancer cases. bcl-2 (protein), p53, and Ki-67 expressions emerged interdependently from this research and can thus be manipulated in prediction and prognosis of breast cancers in our setting.

Keyphrases

binding protein
poor prognosis
protein protein
neoadjuvant chemotherapy
amino acid
endoplasmic reticulum stress
squamous cell carcinoma
cell cycle arrest
signaling pathway
locally advanced