Staphylococcus aureus Efflux Pumps and Tolerance to Ciprofloxacin and Chlorhexidine following Induction by Mupirocin.
Q C Truong-BolducY WangJ L ReedyJatin M VyasDavid C HooperPublished in: Antimicrobial agents and chemotherapy (2021)
Mupirocin induced expression of genes encoding efflux pumps NorA and MepA as well as a yellow fluorescent protein (YFP) fluorescence reporter of NorA. Mupirocin exposure also produced reduced susceptibility to pump substrates ciprofloxacin and chlorhexidine, a change that was dependent on intact norA and mepA , respectively.
Keyphrases
- staphylococcus aureus
- pseudomonas aeruginosa
- poor prognosis
- binding protein
- high glucose
- diabetic rats
- biofilm formation
- crispr cas
- quantum dots
- surgical site infection
- genome wide
- single molecule
- drug induced
- cystic fibrosis
- amino acid
- oxidative stress
- energy transfer
- escherichia coli
- long non coding rna
- dna methylation