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Gait-combined closed-loop brain stimulation can improve walking dynamics in Parkinsonian gait disturbances: a randomised-control trial.

Ippei NojimaMitsuya HoribaKento SahashiSatoko KoganemaruSatona MurakamiKiminori AoyamaNoriyuki MatsukawaYumie OnoTatsuya MimaYoshino Ueki
Published in: Journal of neurology, neurosurgery, and psychiatry (2023)
These findings showed that gait-combined closed-loop tES over the cerebellum improved Parkinsonian gait disturbances, possibly through the modulation of brain networks generating gait rhythms. This new non-pharmacological and non-invasive intervention could be a breakthrough in restoring gait function in patients with PD and related disorders.
Keyphrases
  • cerebral palsy
  • randomized controlled trial
  • clinical trial
  • open label
  • resting state
  • functional connectivity
  • subarachnoid hemorrhage
  • double blind
  • blood brain barrier
  • brain injury