Abdominal fat depots are related to lower cognitive functioning and brain volumes in middle-aged males at high Alzheimer's risk.
Sapir Golan ShekhtmanEthel BoccaraRamit Ravona-SpringerYael InbarHila ZelichaAbigail LivnyBarbara B BendlinOrit H Lesman-SegevIscka YoreAnthony D HeymannMary SanoYael MardorJoseph AzuriMichal Schnaider BeeriPublished in: Obesity (Silver Spring, Md.) (2024)
In middle-aged males at high Alzheimer's dementia risk, but not in females, higher pancreatic fat was associated with lower cognition and brain volumes. These findings suggest a potential sex-specific link between distinct abdominal fat with brain health.