High prevalence of HPV16 and high-grade cytology in women undergoing active surveillance for cervical intraepithelial neoplasia grade 2.
Rikke Kamp DamgaardDavid JenkinsMark H StolerMiekel M van de SandtKathrine Dyhr LyckeMaurits N C de KoningWim G V QuintTorben SteinicheLone Kjeld PetersenAnne HammerPublished in: Acta obstetricia et gynecologica Scandinavica (2023)
The high prevalence of HPV16 and high-grade cytology imply that these women may be perceived as a high-risk population and non-eligible for active surveillance in countries outside Denmark. Future studies should investigate the importance of HPV, age, cytology, and expert review on risk of progression to help refine criteria for active surveillance.