Affective Disorder and Functional Status as well as Selected Sociodemographic Characteristics in Patients with Multiple Sclerosis, Parkinson's Disease and History of Stroke.
Andrzej KnapikEwa KrzystanekJustyna Szefler-DerelaJoanna SiudaJerzy RottermundRyszard PlintaAnna BrzękPublished in: Medicina (Kaunas, Lithuania) (2020)
The main arguments in support of researching anxiety and depression in patients with chronic somatic diseases are the prevalence of affective disorders in the population, somatic conditions as risk factors of affective disorders and the search for effective preventative and therapeutic strategies. The aim of the study was to determine the association between the functional status, selected sociodemographic characteristics and prevalence as well as severity of anxiety and depression in patients with multiple sclerosis (MS), Parkinson's disease (PD) and history of stroke (S). Material and methods: Eighty participants (44 women and 36 men) with MS (n = 22), PD (n = 31) and history of stroke (n = 27) were enrolled. All participants completed a questionnaire consisting of metrics, the Katz Index of Independence in Activities of Daily Living and the Hospital Anxiety and Depression Scale (HADS). Results: Fifty-five per cent of all participants did not present with anxiety or depression, 20% scored above the diagnostic threshold on the anxiety scale and 26% scored above the diagnostic threshold on the depression scale. Subgroup analysis revealed that anxiety and depression sufferers were 13.64% and 13.64% of MS patients, respectively; 22.58% and 35.48% of PD patients, respectively; and 22.22% and 25.93% of stroke survivors, respectively. There was a significant correlation between depression and independence level in the entire group and between depression and marital status in stroke survivors. Conclusions: Although depression and anxiety are highly prevalent in patients with neurological conditions, the disorder has a very individual nature and is not associated with the patient's age, duration of a condition or concomitant diseases. Screening for depression and anxiety as a part of comprehensive approach may increase treatment efficacy in neurological patients.
Keyphrases
- end stage renal disease
- risk factors
- atrial fibrillation
- ejection fraction
- newly diagnosed
- chronic kidney disease
- sleep quality
- depressive symptoms
- multiple sclerosis
- prognostic factors
- ms ms
- peritoneal dialysis
- bipolar disorder
- young adults
- randomized controlled trial
- dna methylation
- type diabetes
- clinical trial
- metabolic syndrome
- genome wide
- adipose tissue
- brain injury
- case report
- skeletal muscle
- copy number
- patient reported
- middle aged
- drug induced
- data analysis