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Enhanced HSC-like cell generation from mouse pluripotent stem cells in a 3D induction system cocultured with stromal cells.

Wei ShanQin YuYan LongQian LuoHonghu LiYingli HanYulin XuShan FuXiangjun ZengCong WeiYang GaoXiaoqing LiXia LiLifei ZhangLizhen LiuMing ChenPengxu QianHe Huang
Published in: Stem cell research & therapy (2021)
Altogether, our findings lay a foundation for improving the efficiency of hematopoietic differentiation and generating in vivo functional HSC-like cells from mouse PSCs for clinical application.
Keyphrases
  • pluripotent stem cells
  • single cell
  • bone marrow
  • cell therapy