Phosphorylated-insulin growth factor I receptor (p-IGF1R) and metalloproteinase-3 (MMP3) expression in advanced gastrointestinal stromal tumors (GIST). A GEIS 19 study.
Joan MaurelAntonio López-PousaSilvia CalabuigSilvia BaguéXavier Garcia Del MuroXavier SanjuanJordi Rubió-CasadevallMiriam CuatrecasasJavier Martinez-TruferoCarlos HorndlerJoaquin FraClaudia ValverdeAndrés RedondoAndrés PovedaIsabel SevillaNuria LainezMichele RubiniXabier García-AlbénizJavier Martín-BrotoEnrique de AlavaPublished in: Clinical sarcoma research (2016)
Our results do not support p-IGF-1R and MMP3 evaluation in non-selected GIST patients but evaluation of this immunophenotype in WT and mutant PDGFR mutation in larger group of GIST patients, deserve merits.