NP-12 peptide functionalized nanoparticles counteract the effect of bacterial lipopolysaccharide on cultured osteoblasts.

Manuel Toledano-OsorioElvira de Luna-BertosManuel ToledanoFrancisco Javier Manzano-MorenoConcepción RuizMariano SanzRaquel Osorio

Published in: Dental materials : official publication of the Academy of Dental Materials (2024)

TDg-NPs on titanium discs counteracted the detrimental effect of LPS by preventing the decrease on osteoblasts proliferation and mineralization, and produced an overexpression of proliferative and bone-promoting genes on human primary osteoblasts.

Keyphrases

endothelial cells
inflammatory response
signaling pathway
cell proliferation
genome wide
toll like receptor
bone mineral density
quantum dots
lps induced
transcription factor
pluripotent stem cells
immune response
gene expression
body composition