Predicting gene expression changes upon epigenomic drug treatment.
Piyush AgrawalVishaka GopalanSridhar HannenhalliPublished in: bioRxiv : the preprint server for biology (2023)
Here we present a first assessment of the predictability of genome-wide transcriptomic changes upon treatment with HDACi. Lack of appropriate omics data from clinical trials of epigenetic drugs currently hampers the assessment of applicability of our approach in clinical setting.