Exhaled breath profiles in the monitoring of loss of control and clinical recovery in asthma.
Paul BrinkmanM A van de PolM G GerritsenL D BosT DekkerB S SmidsA SinhaC J MajoorM M SneeboerH H KnobelT J VinkF H de JonghR LutterP J SterkN FensPublished in: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology (2017)
Loss of asthma control can be discriminated from clinically stable episodes by longitudinal monitoring of exhaled metabolites measured by GC/MS and particularly eNose. Part of the uncovered biomarkers was associated with sputum eosinophils. These findings provide proof of principle for monitoring and identification of loss of asthma control by breathomics.