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Systematic proteomics in Autosomal dominant Alzheimer's disease reveals decades-early changes of CSF proteins in neuronal death, and immune pathways.

Yuanyuan ShenMuhammad AliJigyasha TimsinaCiyang WangAnh DoDaniel WesternMenghan LiuPriyanka GorijalaJohn P BuddeHaiyan LiuBrian A GordonEric McDadeJohn C MorrisJorge Jesus Llibre-GuerraRandell J BatemanNelly Joseph-MathurinRichard J PerrinDario MaschiTony Wyss-CorayPau PastorAlison GoateAlan E RentonEzequiel I SuraceErik C B JohnsonAllan L LeveyIgnacio AlvarezJohannes LevinJohn M RingmanRicardo Francisco AllegriNicholas T SeyfriedGregory S DayQisi WuMaria Victoria Fernandeznull nullIbanez LauraYun Ju SungCruchaga Carlos
Published in: medRxiv : the preprint server for health sciences (2024)
Proteomic data generation was supported by NIH: RF1AG044546.
Keyphrases
  • label free
  • mass spectrometry
  • quantum dots
  • big data
  • highly efficient
  • machine learning
  • cerebrospinal fluid
  • data analysis
  • artificial intelligence
  • mild cognitive impairment