Genomic characterisation of a multidrug-resistant Klebsiella pneumoniae co-harbouring bla NDM-1 , bla KPC-2 , and tet(A) isolated from the bloodstream infections of patients.
Zhijun ZhangRen RenChong PengYingying JiShuang LiuFangkun WangPublished in: International journal of antimicrobial agents (2024)
, and tet(A), and the spread of these genes was mediated by the corresponding mobile elements. The increased carbapenem resistance created by this novel plasmid challenges public health security and poses a potential threat to human health; therefore, it deserves attention.
Keyphrases
- klebsiella pneumoniae
- multidrug resistant
- human health
- escherichia coli
- public health
- drug resistant
- gram negative
- risk assessment
- acinetobacter baumannii
- end stage renal disease
- chronic kidney disease
- newly diagnosed
- climate change
- working memory
- global health
- gene expression
- dna methylation
- genome wide identification