Erythroblast transformation-specific-related gene promotes metastasis of oral squamous cell carcinoma by transcriptionally upregulating peroxiredoxin 1.

Yujia GuXue ChenMei TianKe Liu

Published in: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology (2024)

The transcription factor ERG promotes the expression of PRDX1, which could enhance the proliferation and invasion while inhibiting the apoptosis of OSCC cells.

Keyphrases

cell cycle arrest
transcription factor
induced apoptosis
endoplasmic reticulum stress
cell death
poor prognosis
oxidative stress
pi k akt
signaling pathway
genome wide
copy number
genome wide identification
long non coding rna
binding protein
dna methylation
cell proliferation
gene expression
drug induced