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Duration of Protection against Mild and Severe Disease by Covid-19 Vaccines.

Nick AndrewsElise TessierJulia StoweCharlotte GowerFreja KirsebomRuth SimmonsEileen GallagherSimon ThelwallNatalie GrovesGavin DabreraRichard MyersColin N J CampbellGayatri AmirthalingamMatt EdmundsMaria ZambonKevin E BrownSusan HopkinsMeera ChandShamez N LadhaniMary RamsayJamie Lopez Bernal
Published in: The New England journal of medicine (2022)
We observed limited waning in vaccine effectiveness against Covid-19-related hospitalization and death at 20 weeks or more after vaccination with two doses of the ChAdOx1-S or BNT162b2 vaccine. Waning was greater in older adults and in those in a clinical risk group.
Keyphrases
  • coronavirus disease
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  • randomized controlled trial
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  • systematic review
  • respiratory syndrome coronavirus
  • early onset