Differential expression of STAT3 gene and its regulatory long non-coding RNAs, namely lnc-DC and THRIL, in two eastern Iranian ethnicities with multiple sclerosis.
Majid Pahlevan KakhkiNahid RakhshiMohammad Sajad Emami AleaghaMahla AbdariAsieh AlikhahGhazal SafarianMehrdad BehmaneshMajid Pahlevan KakhkiPublished in: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology (2019)
To our knowledge, this is the first study that compared the expression of the STAT3 gene and its regulatory molecules between two ethnic groups of Iranian MS patients. We suggested that STAT3 and its associated molecules might be differentially expressed and regulated in MS patients with different genetic background.
Keyphrases
- multiple sclerosis
- long non coding rna
- poor prognosis
- genome wide
- transcription factor
- copy number
- end stage renal disease
- cell proliferation
- mass spectrometry
- ms ms
- newly diagnosed
- healthcare
- chronic kidney disease
- prognostic factors
- genome wide identification
- peritoneal dialysis
- white matter
- patient reported outcomes