Effect of adaptive servo-ventilation for central sleep apnoea in systolic heart failure on muscle sympathetic nerve activity: a SERVE-HF randomised ancillary study.
Renaud TamisierJean-Louis PépinHolger WoehrleMuriel SalvatGilles Barone-RochetteCécile RoccaEik VettorazziHelmut TeschlerMartin CowiePatrick LévyPublished in: The European respiratory journal (2022)
Suppression of CSA with ASV did not seem to have a significant effect on chronic HF-related sympathetic activation. Simultaneous suppression of CSA and reduction in MSNA was associated with increased cardiovascular mortality.
Keyphrases
- heart failure
- acute heart failure
- left ventricular
- clinical trial
- blood pressure
- cardiovascular events
- open label
- skeletal muscle
- physical activity
- study protocol
- double blind
- sleep quality
- risk factors
- randomized controlled trial
- cardiovascular disease
- type diabetes
- mechanical ventilation
- depressive symptoms
- positive airway pressure
- coronary artery disease
- cardiac resynchronization therapy
- peripheral nerve
- placebo controlled
- obstructive sleep apnea