Eya2 expression during mouse embryonic development revealed by Eya2lacZ knockin reporter and homozygous mice show mild hearing loss.

Ting ZhangJinshu XuPin-Xian Xu

Published in: Developmental dynamics : an official publication of the American Association of Anatomists (2021)

As Eya2 is coexpressed with other members of the Eya family genes, these results together highlight that Eya2 as a potential regulator may act synergistically with other Eya genes to regulate the differentiation of the inner ear sensory hair cells and the formation of the salivary gland and thymus.

Keyphrases

induced apoptosis
poor prognosis
hearing loss
transcription factor
type diabetes
gene expression
bioinformatics analysis
cell death
adipose tissue
oxidative stress
insulin resistance
cell proliferation
dna methylation
metabolic syndrome
endoplasmic reticulum stress
human health