Multi-omic profiling of intraductal papillary neoplasms of the pancreas reveals distinct expression patterns and potential markers of progression.
Yuefan WangT Mamie LihJae W LeeTakao OhtsukaYuto HozakaMari A Mino-KenudsonN Volkan AdsayClaudio LuchiniAldo ScarpaAjay V MakerGrace E KimJorge PaulinoLijun ChenLiyuan JiaoZhenyu SunDavina GoodmanMichael Johannes PflügerNicholas J RobertsHanno MatthaeiLaura D WoodToru FurukawaHui ZhangRalph H HrubanPublished in: bioRxiv : the preprint server for biology (2024)
This multilevel characterization of intraductal papillary neoplasms of the pancreas provides a foundation for understanding the changes in protein and glycoprotein expression during the progression from normal duct to intraductal papillary neoplasm, and to invasive pancreatic carcinoma, providing a foundation for informed approaches to earlier detection and treatment.