A propensity score-matched analysis of the impact of statin therapy on the outcomes of patients with non-small-cell lung cancer receiving anti-PD-1 monotherapy: a multicenter retrospective study.

Kazuki TakadaMototsugu ShimokawaShinkichi TakamoriShinichiro ShimamatsuFumihiko HiraiTetsuzo TagawaTatsuro OkamotoMotoharu HamatakeYuko Tsuchiya-KawanoKohei OtsuboKoji InoueYasuto YoneshimaKentaro TanakaIsamu OkamotoYoichi NakanishiMasaki Mori

Published in: BMC cancer (2022)

Statin therapy may be a combination tool for cancer immunotherapy in patients with NSCLC. These findings should be validated in further prospective studies with larger sample sizes.

Keyphrases

cardiovascular disease
coronary artery disease
small cell lung cancer
stem cells
metabolic syndrome
open label
cross sectional
combination therapy
bone marrow
insulin resistance
weight loss
replacement therapy