Prevention of anastomotic leak in rectal cancer surgery with local antibiotic decontamination: a prospective, randomized, double-blind, placebo-controlled single center trial.
H M SchardeyUlrich WirthT StraussM S KasparekD SchneiderK W JauchPublished in: International journal of colorectal disease (2020)
Local decontamination with polymyxin, tobramycin, vancomycin, and amphotericin B is safe and effective in the prevention of anastomotic leak in rectal cancer surgery.
Keyphrases
- rectal cancer
- placebo controlled
- double blind
- locally advanced
- minimally invasive
- phase iii
- coronary artery bypass
- study protocol
- phase ii
- clinical trial
- surgical site infection
- phase ii study
- randomized controlled trial
- open label
- squamous cell carcinoma
- multidrug resistant
- staphylococcus aureus
- gram negative
- acute coronary syndrome