Major adverse cardiovascular events and mortality with opioids versus NSAIDs initiation in patients with rheumatoid arthritis.
Gulsen OzenSofia PedroKaleb D MichaudPublished in: Annals of the rheumatic diseases (2023)
Opioids had similar MACE risk compared with NSAIDs in patients with RA with increased all-cause mortality and likely VTE, which suggests that opioids are not safer than NSAIDs, as clinicians have perceived.
Keyphrases
- cardiovascular events
- chronic pain
- pain management
- coronary artery disease
- anti inflammatory drugs
- cardiovascular disease
- venous thromboembolism
- rheumatoid arthritis
- depressive symptoms
- social support
- physical activity
- palliative care
- mental health
- type diabetes
- disease activity
- interstitial lung disease
- systemic lupus erythematosus
- systemic sclerosis
- electronic health record
- adverse drug
- drug induced