A systematic review and meta-analysis to evaluate the diagnostic accuracy of PSMA PET/CT in the initial staging of prostate cancer.
Andrea MariAnna CadenarSofia GiudiciGemma CianchiSimone AlbisinniRiccardo AutorinoFabrizio Di MaidaGiorgio GandagliaMaria Carmen Mir MaresmaMassimo ValerioGiancarlo MarraFabio ZattoniLorenzo BianchiRiccardo LombardoShahrokh F ShariatMorgan RoupretMatteo BaucknehtLuca VaggelliCosimo De NunzioAndrea MinerviniPublished in: Prostate cancer and prostatic diseases (2024)
The present systematic review and meta-analysis highlights PSMA PET-CT effectiveness in detecting SVI and its good accuracy in LNI compared to CI. Nonetheless, it also reveals a lack of high-quality research on its performance in clinical T staging, extraprostatic extension and distant metastasis evaluation, emphasizing the need for further rigorous studies.