GFAP palmitoylcation mediated by ZDHHC23 in spinal astrocytes contributes to the development of neuropathic pain.

Xiaoqing FanSiyu ZhangSuling SunWenxu BiShuyang LiWei WangXueran ChenZhiyou Fang

Published in: Regional anesthesia and pain medicine (2023)

In a rodent model, targeting GFAP palmitoylation appears to be an effective strategy in relieving cancer pain and morphine tolerance. Human translational research is warranted.

Keyphrases

neuropathic pain
spinal cord
spinal cord injury
endothelial cells
papillary thyroid
squamous cell
cancer therapy
pluripotent stem cells
lymph node metastasis
squamous cell carcinoma