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Fibroblast growth factor 19 as a countermeasure to muscle and locomotion dysfunctions in experimental cerebral palsy.

Sabrina da Conceição PereiraBérengère BenoitFrancisco Carlos Amanajás de Aguiar JuniorStephanie ChanonAurélie Vieille-MarchisetSandra PesentiJérome RuzzinHubert VidalAna Elisa Toscano
Published in: Journal of cachexia, sarcopenia and muscle (2021)
These results demonstrate that pharmacological intervention with recombinant FGF19 could restore musculoskeletal and locomotor dysfunction in an experimental CP model, suggesting that FGF19 may represent a potential therapeutic strategy to combat the locomotor disorders associated with CP.
Keyphrases
  • cerebral palsy
  • spinal cord injury
  • randomized controlled trial
  • skeletal muscle
  • oxidative stress