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High-content image-based CRISPR screening reveals regulators of 3D genome architectures.

Mengwei HuBing YangTyler B JensenJonathan S D RaddaYubao ChengShengyan JinSiyuan Wang
Published in: bioRxiv : the preprint server for biology (2023)
CRISPR screen, cellular barcoding, and chromatin tracing identify regulators of higher-order chromatin organization.
Keyphrases
  • genome wide
  • transcription factor
  • dna methylation
  • genome editing
  • crispr cas
  • deep learning
  • high throughput
  • gene expression
  • dna damage
  • machine learning
  • oxidative stress