Association Between Atrial Uptake on Cardiac Scintigraphy With Technetium-99m-Pyrophosphate Labeled Bone-Seeking Tracers and Atrial Fibrillation.
Muzna HussainAlison R KrywanczykEoin DonnellanTrejeeve MartynOssama Abou HassanSaqer AlkharabshehChris WatsonWai Hong Wilson TangDeborah KwonPaul C CremerFeixiong ChengMohamed KanjBrian P GriffinCarmela D TanE Rene RodriguezMazen HannaWael A JaberPatrick H CollierPublished in: Circulation. Cardiovascular imaging (2022)
In a consecutive cohort of patients undergoing 99mTc-PyP scans, 20% had AU, which was statistically associated with any AF, independently of ATTR-CA diagnosis and sex. AU was associated with significantly lower freedom from incident AF at 1-year. Overlooking AU on 99mTc-PyP scans could potentially miss an earlier disease manifestation, or an additional risk factor for any/incident AF.
Keyphrases
- atrial fibrillation
- sensitive detection
- catheter ablation
- left atrial
- patients undergoing
- oral anticoagulants
- reduced graphene oxide
- left atrial appendage
- computed tomography
- cardiovascular disease
- direct oral anticoagulants
- heart failure
- percutaneous coronary intervention
- mental health
- left ventricular
- contrast enhanced
- quantum dots
- pet imaging
- gold nanoparticles
- pet ct
- visible light
- magnetic resonance imaging
- venous thromboembolism
- coronary artery disease
- soft tissue
- mitral valve