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Proteomic profiling of FBXW7-mutant serous endometrial cancer cells reveals upregulation of PADI2, a potential therapeutic target.

Mary Ellen UrickDaphne W Bell
Published in: Cancer medicine (2020)
Our findings provide novel insight into proteomic changes associated with FBXW7 mutation in serous ECs and identify PADI2 as a novel potential therapeutic target for these tumors.
Keyphrases
  • high grade
  • human health
  • cell proliferation
  • label free
  • poor prognosis
  • single cell
  • risk assessment
  • endometrial cancer