Infarct Evolution on MR-DWI After Thrombectomy in Acute Stroke Patients Randomized to Nerinetide or Placebo: The REPERFUSE-NA1 Study

Joachim C Fladt Jen Guo Jacinta L Specht Meng Wang Leona L ChanRyan MctaggartBrian H Buck Richard I Aviv Richard H Swartz Thalia Shoshana FieldJason TarpleyRuchir ShahMayank Goyal Michael Tymianski Michael D Hill Andrew M DemchukChristopher d'EsterrePhilip A Barber

Published in: Neurology (2023)

This study provides Class II evidence that for patients with acute large vessel ischemic stroke undergoing EVT, nerinetide did not significantly decrease early post-EVT infarct growth compared with placebo.

Keyphrases

double blind
phase iii
placebo controlled
randomized controlled trial
clinical trial
magnetic resonance
heart failure
liver failure
atrial fibrillation
computed tomography
coronary artery disease
acute coronary syndrome
intensive care unit
drug induced
left ventricular
phase ii
acute ischemic stroke