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Novel venom-based peptides (P13 and its derivative-M6) to maintain self-renewal of human embryonic stem cells by activating FGF and TGFβ signaling pathways.

Rui MaZhili RenBin LiShirley W I SiuGuokai ChenHang Fai Kwok
Published in: Stem cell research & therapy (2020)
Taken together, this study is the first research finding on a venom-based peptide that works on the FGF and TGF-β signaling pathways to maintain the self-renewal of hESCs.
Keyphrases
  • signaling pathway
  • embryonic stem cells
  • transforming growth factor
  • endothelial cells
  • epithelial mesenchymal transition
  • pi k akt
  • induced apoptosis
  • pluripotent stem cells
  • amino acid