CYTOTOXIC EFFECTS OF DULOXETINE ON MKN45 AND NIH3T3 CELL LINES AND GENOTOXIC EFFECTS ON HUMAN PERIPHERAL BLOOD LYMPHOCYTES.

Melika Hassani Nasrin Ghassemi Barghi Faezeh Modanloo Abbas Mohammadpour Mohammad Shokrzadeh

Published in: Arquivos de gastroenterologia (2020)

Although, in this study, duloxetine had less genotoxicity than cisplatin in concentrations under 200 μM and showed cytotoxic effects as well, due to its IC50, it cannot be considered as a better choice for gastric cancer therapies with respect to cisplatin as a common anticancer drug.

Keyphrases

peripheral blood
endothelial cells
induced pluripotent stem cells
emergency department
pluripotent stem cells
decision making
drug induced
electronic health record