Systematic review of data-driven cognitive subtypes in Parkinson disease.
Dana PourzinalJihyun YangRachael A LawsonKatie L McMahonGerard J ByrneNadeeka N W DissanayakaPublished in: European journal of neurology (2022)
Recurring phenotypes in the literature suggest strong clinical relevance of certain cognitive subtypes in PD. Although the current literature is limited, it raises critical questions about the utility of data-driven methods in cognitive research. The results encourage further integration of neuroimaging research to define the latent neural mechanisms behind divergent subtypes. Although there is no consensus, there appears to be growing consistency and inherent value in identifying cognitive subtypes in PD.