Loading history changes the morphology and compressive force-induced expression of receptor activator of nuclear factor kappa B ligand/osteoprotegerin in MLO-Y4 osteocytes.

Ziyi WangYao WengYoshihito IshiharaNaoya OdagakiEi Ei Hsu HlaingTakashi IzawaHirohiko OkamuraHiroshi Kamioka

Published in: PeerJ (2020)

Our findings indicated that the compressive force-induced changes in the RANKL/OPG expression could be habituated within at least 11 h by 36-h CCF exposure. GJIC and cell morphology may play roles in response to loading history in MLO-Y4 osteocyte-like cells.

Keyphrases

nuclear factor
toll like receptor
poor prognosis
single molecule
binding protein
single cell
diabetic rats
high glucose
immune response
stem cells
mesenchymal stem cells
stress induced
bone loss