Apigenin-Loaded Solid Lipid Nanoparticle Attenuates Diabetic Nephropathy Induced by Streptozotocin Nicotinamide Through Nrf2/HO-1/NF-kB Signalling Pathway.
Pingping LiSyed Nasir Abbas BukhariTahseen KhanRenukaradhya ChittiDavan B BevoorAnand R HiremathSreeharsha NagarajaYogendra SinghKumar Shiva GubbiyappaPublished in: International journal of nanomedicine (2020)
We found that a protective effect on diabetic nephropathy was shown due to Apigenin-SLNPs, in rats induced with streptozocin maybe through the pathway of nuclear factor erythroid 2-related factor 2/heme oxygenase-1/Nuclear Factor-κB.
Keyphrases
- nuclear factor
- diabetic nephropathy
- toll like receptor
- diabetic rats
- oxidative stress
- high glucose
- drug delivery
- drug induced
- cancer therapy
- inflammatory response
- type diabetes
- fatty acid
- immune response
- signaling pathway
- metabolic syndrome
- wound healing
- adipose tissue
- cell proliferation
- high fat diet
- insulin resistance