Tumor dynamic model-based decision support for Phase Ib/II combination studies: A retrospective assessment based on resampling of the Phase III study IMpower150.
René BrunoMathilde MarchandKenta YoshidaPhyllis ChanHaocheng LiWei ZouFrancois MercierPascal ChanuBenjamin WuAnthony LeeChunze LiJin Yan JinMichael L MaitlandMartin ReckMark A SocinskiPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Model-based estimate of KG GMR is an exploratory endpoint that informs early clinical decisions for combination studies.